TY - JOUR T1 - Transient increase in DNA strand breaks in car refinishing spray painters JO - Scandinavian Journal of Work, Environment & Health PY - 1996/12VL - 22 IS - 6 SP - 438 EP - 443 AU - Fuchs, J AU - Hengstler, JG AU - Hummrich, F AU - Oesch, F M3 - doi: 10.5271/sjweh.165 UR - https://www.sjweh.fi/show_abstract.php?abstract_id=165 KW - alkaline elution KW - biomonitoring KW - DNA damage KW - human mononuclear blood cells KW - safety provision N2 - '

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OBJECTIVES ': 'Genotoxic risk was evaluated for spray painters possibly exposed to polyester resins and acrylic enamel-based paints in automotive body repair shops.'

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METHODS ': 'DNA (deoxyribonucleic acid) strand breaks and alkali-labile sites were measured in peripheral mononuclear blood cells ex vivo using the alkaline elution method. Samples of venous blood were taken on Monday after a free weekend and again on Friday from 38 male and 1 female spray painters and compared with the blood samples from 36 male and 3 female referents. The elution rate of each DNA sample was standardized by dividing it by the elution rate obtained from simultaneously sampled untreated Chinese hamster V79 cells.'

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RESULTS ': 'The spray painters showed a significantly (P SN - 0355-3140 ER -