@Article{Siegel1991, author = "Siegel, P. D. and Olenchock, S. A. and Sorenson, W. G. and Lewis, D. M. and Bledsoe, T. A. and May, J. J. and Pratt, D. S.", title = "Histamine and endotoxin contamination of hay and respirable hay dust.", journal = "Scandinavian Journal of Work, Environment & Health", year = "1991", month = "Aug", day = "17", number = "4", pages = "276--280", abstract = "
Three distinct samples collected from a barn in which an outbreak of respiratory problems occurred were examined for possible etiologic agents. No causal relationship could be established from the results of this study; however histamine concentrations as high as 0.5 ng/mg for bulk hay (in the absence of measurable creatinine levels) along with 6138.3 endotoxin units/mg of hay were present in the samples. Both endotoxin and histamine could be recovered from respirable hay dust. The authenticity of the histamine found in the hay was evaluated with high-performance liquid chromatography and radioimmunoassay. Histamine release caused by hay extracts was evaluated with the use of leukocytes from the farmer and a referent. Histamine is known to modulate the immune system, but the role of occupational or environmental exposure to histamine in respiratory disease is unknown.
", issn = "0355-3140", doi = "10.5271/sjweh.1702", url = "https://www.sjweh.fi/show_abstract.php?abstract_id=1702", url = "https://doi.org/10.5271/sjweh.1702" }