@Article{Kiilunen1983, author = "Kiilunen, M. and Kivisto, H. and Ala-Laurila, P. and Tossavainen, Antti and Aitio, Antero", title = "Exceptional pharmacokinetics of trivalent chromium during occupational exposure to chromium lignosulfonate dust.", journal = "Scandinavian Journal of Work, Environment & Health", year = "1983", month = "Jun", day = "9", number = "3", pages = "265--271", abstract = "
The excretion of chromium in the urine of workers exposed to chromium lignosulfonate was studied. The chromium in the dust was in the trivalent (III) oxidation state, and 30% of the particles were less than 5 micron in diameter. Chromium (III) lignosulfonate dust was rapidly absorbed, and a peak of urinary excretion was seen immediately after exposure. No appreciable accumulation of chromium occurred over 3 d, as evaluated by comparison with preshift urinary chromium concentrations. The addition of ethylenediaminetetra-acetate to the urine of exposed persons greatly enhanced the capacity of chromium to traverse a dialysis membrane; the same effect was seen with chromium (III) chloride. It is concluded that chromium (III) lignosulfonate yields chromium (III), which acts pharmacokinetically like water-soluble hexavalent chromium compounds.
", issn = "0355-3140", doi = "10.5271/sjweh.2410", url = "https://www.sjweh.fi/show_abstract.php?abstract_id=2410", url = "https://doi.org/10.5271/sjweh.2410" }