@Article{Stewart1976,
author = "Stewart, Richard D.
and Hake, Carl L.
and Wu, Anthony",
title = "Use of breath analysis to monitor methylene chloride exposure.",
journal = "Scandinavian Journal of Work, Environment & Health",
year = "1976",
month = "Jun",
day = "2",
number = "2",
pages = "57--70",
keywords = "breath analysis; exposure; methylene chloride; methylene chloride exposure; occupational monitoring",
abstract = "
Twenty male and female subjects were exposed repetitively to methylene chloride (CH2Cl2) vapor, 50, 100, 250, and 500 ppm, for 1,3, or 7.5 h in a controlled-environment chamber. Postexposure alveolar breath samples were collected in small glass breath tubes and analyzed for CH2Cl2 by gas chromatography. From these data is a series of breath CH2Cl2 excretion curves were constructed that can be used to estimate the magnitude of a recent exposure. The CH2Cl2 breath concentration in the immediate postexposure period accurately reflected the vapor concentration to which the subjects had been exposed most recently. Breath samples collected 1-2 h following exposure were accurate indicators of the time-weighted average vapor exposure experienced by the subjects during the previous 8 h of occupational exposure. Breath analysis offers a practical, noninvasive method for monitoring occupational exposure to CH2Cl2.
",
issn = "0355-3140",
doi = "10.5271/sjweh.2817",
url = "https://www.sjweh.fi/show_abstract.php?abstract_id=2817",
url = "https://doi.org/10.5271/sjweh.2817"
}