%0 Journal Article
%T Use of breath analysis to monitor methylene chloride exposure.
%A Stewart, Richard D.
%A Hake, Carl L.
%A Wu, Anthony
%J Scandinavian Journal of Work, Environment & Health
%D 1976
%8 June 2
%N 2
%@ 0355-3140
%F Stewart1976
%X
Twenty male and female subjects were exposed repetitively to methylene chloride (CH2Cl2) vapor, 50, 100, 250, and 500 ppm, for 1,3, or 7.5 h in a controlled-environment chamber. Postexposure alveolar breath samples were collected in small glass breath tubes and analyzed for CH2Cl2 by gas chromatography. From these data is a series of breath CH2Cl2 excretion curves were constructed that can be used to estimate the magnitude of a recent exposure. The CH2Cl2 breath concentration in the immediate postexposure period accurately reflected the vapor concentration to which the subjects had been exposed most recently. Breath samples collected 1-2 h following exposure were accurate indicators of the time-weighted average vapor exposure experienced by the subjects during the previous 8 h of occupational exposure. Breath analysis offers a practical, noninvasive method for monitoring occupational exposure to CH2Cl2.
%K breath analysis
%K exposure
%K methylene chloride
%K methylene chloride exposure
%K occupational monitoring
%R 10.5271/sjweh.2817
%U https://www.sjweh.fi/show_abstract.php?abstract_id=2817
%U https://doi.org/10.5271/sjweh.2817
%P 57-70