TY - JOUR T1 - β€œIs this case of a very rare disease work-related?” A review of reported cases of Pacinian neuroma JO - Scandinavian Journal of Work, Environment & Health PY - 2011/5VL - 37 IS - 3 SP - 253 EP - 258 AU - Zanardi, Francesca AU - Cooke, Robin MT AU - Maiorana, Antonino AU - Curti, Stefania AU - Farioli, Andrea AU - Bonfiglioli, Roberta AU - Violante, Francesco S AU - Mattioli, Stefano M3 - doi: 10.5271/sjweh.3132 UR - https://www.sjweh.fi/show_abstract.php?abstract_id=3132 KW - hand injury KW - mechanoreceptors pathology KW - occupational exposure KW - pacinian corpuscles KW - Pacinian neuroma KW - work-related N2 - '

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OBJECTIVE ': 'In response to a request for a medicolegal opinion from an orthopaedic technician with pacinian neuroma of the hand, we conducted a systematic review of reported cases designed to assess whether this rare disease could be considered to be work-related.

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METHODS ': 'We used Medline, Embase, Google Scholar, Google, and a manual search to identify reports of histologically confirmed pacinian neuroma of the hand manifesting after 15 years of age. Cases with available information (from article/authors) on personal history were considered eligible. We tabulated information on age/gender; localization and histopathologic features; signs/symptoms; history of local trauma; occupation, sports/hobbies or other physical exposures; right- or left-handedness; and outcome.

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RESULTS ': 'We found 44 eligible cases (including the present referral). Of these, 21 (48%) followed a trauma [<6 months from onset/presentation (N=7); 0.5–2 years from onset (N=6); β‰₯2 years from onset (N=7); and timing unknown (N=1)] involving the same anatomic site. Three of these 21 traumas definitely occurred at work, and a further 2 cases occurred at the site of definite work-related repetitive microtrauma.

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CONCLUSIONS ': 'The results reinforce the concept that pacinian neuroma of the hand can follow local trauma or repetitive microtrauma. Implicated traumas were either recent or remote, and they sometimes occurred while performing manual tasks at work. We concluded that the referred case could plausibly be considered work-related.

SN - 0355-3140 ER -