%0 Journal Article %T Economic evaluation of a randomized controlled trial of an intervention to reduce office workers’ sitting time: the "Stand Up Victoria" trial %A Gao, Lan %A Flego, Anna %A Dunstan, David W. %A Winkler, Elisabeth AH %A Healy, Genevieve N. %A Eakin, Elizabeth G. %A Willenberg, Lisa %A Owen, Neville %A LaMontagne, Anthony D. %A Lal, Anita %A Wiesner, Glen H. %A Hadgraft, Nyssa T. %A Moodie, Marj L. %J Scandinavian Journal of Work, Environment & Health %D 2018 %8 September 44 %N 5 %@ 0355-3140 %F Gao2018 %X '

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OBJECTIVES ': 'This study aimed to assess the economic credentials of a workplace-delivered intervention to reduce sitting time among desk-based workers.

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METHODS ': 'We performed within-trial cost-efficacy analysis and long-term cost-effectiveness analysis (CEA) and recruited 231 desk-based workers, aged 24–65 years, across 14 worksites of one organization. Multicomponent workplace-delivered intervention was compared to usual practice. Main outcome measures including total device-measured workplace sitting time, body mass index (BMI), self-reported health-related quality of life (Assessment of Quality of Life-8D, AQoL-8D), and absenteeism measured at 12 months.

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RESULTS ': 'Compared to usual practice, the intervention was associated with greater cost (AU$431/person), benefits in terms of reduced workplace sitting time [-46.8 minutes/8-hour workday, 95% confidence interval (CI): -69.9– -23.7] and increased workplace standing time (42.2 minutes/8-hour workday, 95% CI 23.8–60.6). However, there were no significant benefits for BMI [0.148 kg/m2 (95% CI-1.407–1.703)], QoL-8D [-0.006 (95% CI -0.074–0.063)] and absenteeism [2.12 days (95% CI -2.01–6.26)]. The incremental cost-efficacy ratios (ICER) ranged from AU$9.94 cost/minute reduction in workplace sitting time to AU$13.37/minute reduction in overall sitting time. CEA showed the intervention contributed to higher life year (LY) gains [0.01 (95% CI 0.009–0.011)], higher health-adjusted life year (HALY) gains [0.012 (95% CI 0.0105 – 0.0135)], and higher net costs [AU$344 (95% CI $331–358)], with corresponding ICER of AU$34 443/LY and AU$28 703/HALY if the intervention effects were to be sustained for five-years. CEA results were sensitive to assumptions surrounding intervention-effect decay rate and discount rate.

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CONCLUSIONS ': 'The intervention was cost-effective over the lifetime of the cohort when scaled up to the national workforce and provides important

%K cost-effectiveness analysis %K cost-efficacy %K economic evaluation %K evaluation %K intervention %K office worker %K productivity %K randomized controlled trial %K RCT %K sit-stand workstation %K sitting %K sitting time %K Stand-Up Victoria %K workplace intervention %R 10.5271/sjweh.3740 %U https://www.sjweh.fi/show_abstract.php?abstract_id=3740 %U https://doi.org/10.5271/sjweh.3740 %P 503-511