@Article{Sjgren1999, author = "Sjögren, Bengt and Wang, Z. and Larsson, Britt-Marie and Larsson, Kjell and Larsson, P. H. and Westerholm, Peter", title = "Increase in interleukin-6 and fibrinogen in peripheral blood after swine dust inhalation", journal = "Scandinavian Journal of Work, Environment & Health", year = "1999", month = "Feb", day = "25", number = "1", pages = "39--41", keywords = "endotoxin", abstract = "'
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OBJECTIVES ': 'The inhalation of dust from swine confinement buildings causes inflammatory responses in the airways with a rise of interleukin-6 (IL-6). The purpose of this study was to confirm the increase in serum IL-6 after inhalation of swine dust and investigate a possible increase in plasma fibrinogen.'
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METHODS ': 'Eight healthy nonsmoking volunteers inhaled dust for 4 hours inside a swine confinement building. Inhalable dust and endotoxin were sampled. The concentrations of IL-6 and fibrinogen were determined in serum and plasma.'
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RESULTS ': 'The study showed a clear increase in the concentrations of IL-6 and fibrinogen after exposure.'
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CONCLUSION ': 'As fibrinogen is an important risk factor for ischemic heart disease, the increased concentration of fibrinogen among persons exposed to swine dust may increase the risk for this disease.
", issn = "0355-3140", doi = "10.5271/sjweh.381", url = "https://www.sjweh.fi/show_abstract.php?abstract_id=381", url = "https://doi.org/10.5271/sjweh.381" }