@Article{Torn1999, author = "Torén, Kjell and Järvholm, Bengt and Brisman, Jonas Brisman and Hagberg, Stig and Hermansson, B.-A. and Lillienberg, Linnéa", title = "Adult-onset asthma and occupational exposures", journal = "Scandinavian Journal of Work, Environment & Health", year = "1999", month = "Oct", day = "25", number = "5", pages = "430--435", keywords = "asthma; epidemiology; questionnaire; retrospective study", abstract = "'
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OBJECTIVES ': 'This study examined certain occupational exposures and the risk for adult-onset asthma.'
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METHODS ': 'A nested case-referent study of adult-onset asthma was performed on a random population sample (N=15 813), aged 21 to 51 years. Cases for the study included 2 groups: subjects reporting ``physician-diagnosed'' asthma (N=251) and a broader ``asthma'' group (N=362). The ``asthma'' group consisted of subjects with ``physician-diagnosed'' asthma (N=251) and subjects reporting asthma-like symptoms without having ``physician-diagnosed'' asthma (N=111). The referents (N=2044) were randomly selected from the whole population sample. The case-referent sample was investigated with a comprehensive questionnaire about occupational exposures, asthma, respiratory symptoms, smoking, and atopy. Odds ratios were calculated with stratification for gender, year of diagnosis, and birth year.'
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RESULTS ': 'The highest odds ratio for ``physician-diagnosed'' asthma was associated with exposure to flour dust [odds ratio (OR) 2.8, 95% confidence interval (95% CI) 1.5--5.2] and the occupational handling of resin-based paints (isocyanates) (OR 3.0, 95% CI 1.6--5.9). Exposure to welding fumes, textile dust, and work with glues containing acrylates was also associated with an increased odds ratio for ``physician-diagnosed'' asthma. Including persons with asthma-like symptoms (ie, the asthma group) showed similar results.'
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CONCLUSION ': 'This population-based case-referent study from Sweden indicates that occupational exposure to acrylate-based compounds and welding fumes is associated with increased risk for adult-onset asthma.
", issn = "0355-3140", doi = "10.5271/sjweh.456", url = "https://www.sjweh.fi/show_abstract.php?abstract_id=456", url = "https://doi.org/10.5271/sjweh.456" }