%0 Journal Article %T Adult-onset asthma and occupational exposures %A Torén, Kjell %A Järvholm, Bengt %A Brisman, Jonas Brisman %A Hagberg, Stig %A Hermansson, B.-A. %A Lillienberg, Linnéa %J Scandinavian Journal of Work, Environment & Health %D 1999 %8 October 25 %N 5 %@ 0355-3140 %F Torén1999 %X '

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OBJECTIVES ': 'This study examined certain occupational exposures and the risk for adult-onset asthma.'

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METHODS ': 'A nested case-referent study of adult-onset asthma was performed on a random population sample (N=15 813), aged 21 to 51 years. Cases for the study included 2 groups: subjects reporting "physician-diagnosed" asthma (N=251) and a broader "asthma" group (N=362). The "asthma" group consisted of subjects with "physician-diagnosed" asthma (N=251) and subjects reporting asthma-like symptoms without having "physician-diagnosed" asthma (N=111). The referents (N=2044) were randomly selected from the whole population sample. The case-referent sample was investigated with a comprehensive questionnaire about occupational exposures, asthma, respiratory symptoms, smoking, and atopy. Odds ratios were calculated with stratification for gender, year of diagnosis, and birth year.'

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RESULTS ': 'The highest odds ratio for "physician-diagnosed" asthma was associated with exposure to flour dust [odds ratio (OR) 2.8, 95% confidence interval (95% CI) 1.5--5.2] and the occupational handling of resin-based paints (isocyanates) (OR 3.0, 95% CI 1.6--5.9). Exposure to welding fumes, textile dust, and work with glues containing acrylates was also associated with an increased odds ratio for "physician-diagnosed" asthma. Including persons with asthma-like symptoms (ie, the asthma group) showed similar results.'

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CONCLUSION ': 'This population-based case-referent study from Sweden indicates that occupational exposure to acrylate-based compounds and welding fumes is associated with increased risk for adult-onset asthma.

%K asthma %K epidemiology %K questionnaire %K retrospective study %R 10.5271/sjweh.456 %U https://www.sjweh.fi/show_abstract.php?abstract_id=456 %U https://doi.org/10.5271/sjweh.456 %P 430-435