TY - JOUR T1 - Shift work and the risk of diabetes mellitus among Japanese male factory workers JO - Scandinavian Journal of Work, Environment & Health PY - 2005/6VL - 31 IS - 3 SP - 179 EP - 183 AU - Morikawa, Yuko AU - Nakagawa, Hideaki AU - Miura, Katsuyuki AU - Soyama, Yoshiyuki AU - Ishizaki, Masao AU - Kido, Teruhiko AU - Naruse, Yuchi AU - Suwazono, Yasushi AU - Nogawa, Koji M3 - doi: 10.5271/sjweh.867 UR - https://www.sjweh.fi/show_abstract.php?abstract_id=867 KW - cohort study KW - diabetes mellitus KW - factory worker KW - glucose tolerance KW - glycated hemoglobin KW - Japan KW - man KW - shift work N2 - '

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OBJECTIVES ': 'This study investigated whether shift work is a risk factor for the development of diabetes mellitus.

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METHODS ': 'The workers, 2860 men in a sash and zipper factory in the Toyama prefecture of Japan, were followed for 8 years, and the incidence rate of diabetes mellitus was determined. The cohort contained fixed daytime blue-collar workers, shift blue-collar workers, and white-collar workers. The workers were considered to have diabetes mellitus if, in their annual health examination, they had a glycated hemoglobin level of ≥6.1 or if the diagnosis had been made by a hospital physician. The relative risks were estimated by Cox’s proportional hazards regression model.

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RESULTS ': 'Among the 2860 workers, there were 87 cases of new-onset diabetes mellitus, resulting in an incidence rate of 4.41 per 1000 person-years. The age-adjusted incidence was highest for the two-shift workers and lowest for the white-collar workers. The relative risk of diabetes mellitus for the two-shift workers and the three-shift workers compared with the fixed daytime workers was 1.73 and 1.33, respectively, after adjustment for all the confounding factors, but these values were not statistically significant. When the white-collar workers were used as a reference group, a significantly increased risk of diabetes mellitus was found for the two-shift workers (relative risk was 2.01 after adjustment for all confounding factors), but not for the three-shift workers or the fixed daytime blue-collar workers.

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CONCLUSIONS ': 'The study suggests that shift work is a risk factor for the onset of diabetes mellitus and that there is a different risk associated with different shift schedules.

SN - 0355-3140 ER -