@Article{Ambroise2006, author = "Ambroise, Denis and Wild, Philipp and Moulin, Jean-Jacques", title = "Update of a meta-analysis on lung cancer and welding", journal = "Scandinavian Journal of Work, Environment & Health", year = "2006", month = "Feb", day = "32", number = "1", pages = "22--31", keywords = "epidemiologic study; heterogeneity; lung cancer; meta-analysis; publication bias; stainless steel; welding", abstract = "'
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OBJECTIVES ': 'This study is an update, over the period 1954–2004, of a previous meta-analysis completed in 1994. It was aimed at assessing lung cancer risk among welders, while addressing heterogeneity, publication bias, and confounding issues.
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METHODS ': 'Combined relative risks (CRR) and their variances were calculated using fixed and random effects models. Heterogeneity was tested using the Q statistic. The publication bias was estimated using funnel plots, and Egger’s regression and partially controlled by excluding studies with positive reporting bias.
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RESULTS ': 'The literature provided 60 studies eligible for the meta-analysis. No heterogeneity was observed. The fixed effect CRR for all of the welders and all of the studies was 1.26 (95% CI 1.20–1.32) after partial control of publication bias. No difference was observed according to welding activities. Smoking did not appear to be a marked confounder in the relationship between lung cancer and welding, but the effect of asbestos could not be assessed.
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CONCLUSIONS ': 'The meta-analysis showed a 26% excess of lung cancer for welders without any difference according to welding activities.
", issn = "0355-3140", doi = "10.5271/sjweh.973", url = "https://www.sjweh.fi/show_abstract.php?abstract_id=973", url = "https://doi.org/10.5271/sjweh.973" }