SJWEH - Online-first articles List of Online-first articles on the SJWEH website http://www.sjweh.fi/list_onlinefirst_rss.php en-US SJWEH 1 lodo@ttl.fi (Lisa O\'Donoghue-Lindy) risto@toivonen.biz (Risto Toivonen) Night shift work and the acceleration of chronic kidney disease onset: dose–response relationships, interactions with cardiometabolic genetic risk, and metabolomic mediators http://www.sjweh.fi/show_abstract.php?abstract_id=4296 http://www.sjweh.fi/show_abstract.php?abstract_id=4296 Mon, 25 May 2026 12:23:42 +0200 Original article adj) 1.25, 95% confidence interval (CI) 1.10–1.41] and developed CKD 2.06 years earlier (95% CI 0.75–3.25). Lifetime night shift exposure showed consistent dose–response relationships, with 16–17% increased risks for either ≥5 cumulative years (HRadj 1.17, 95% CI1.01–1.36) or ≥3 monthly night shifts (HRadj 1.16, 95% CI1.01–1.33). Participants with both usual/always night shift exposure and high PRS for cardiometabolic diseases exhibited the greatest CKD risk. Obesity-related parameters (body mass index and waist circumference) mediated 14.7–14.8% of the observed night shift–CKD association. A novel 9-metabolite signature reflective of night shift mediated 5.47% of this association, primarily through disrupted fatty acid metabolism. Conclusions Night shift work exhibits a dose-dependent association with CKD risk, exacerbated by cardiometabolic genetic predisposition and partially mediated through metabolic dysregulation and obesity. These findings underscore the need for workplace interventions targeting shift scheduling and metabolic health among high-risk workers. by Cai X, Zhang Y, Ye Z, Yang S, Gan X, Xiang H, Huang Y, Wu Y, Chen D, Liang X, Qin X. doi:10.5271/sjweh.4309]]> Night shift work and breast cancer risk: A cohort study based on payroll and survey data from Finland http://www.sjweh.fi/show_abstract.php?abstract_id=4309 http://www.sjweh.fi/show_abstract.php?abstract_id=4309 Wed, 20 May 2026 16:55:43 +0200 Original article 3 consecutive night shifts [hazard ratio (HR) 1.64, 95% confidence interval (CI) 1.22–2.21] and evening shifts (HR 1.28, 95% CI 1.03–1.59). Sleep problems and fatigue at work modified the association between night shift work and breast cancer risk, whereas psychological distress and diurnal preference did not. Permanent night shift workers reporting sleep problems (HR 1.76, 95% CI 1.01–3.09) or fatigue at work (HR 1.90, 95% CI 1.08–3.35) had a higher risk compared to day workers with similar symptoms. Conclusions Women aged ≥50 years showed increased breast cancer risk for several shift work characteristics. Permanent night shift work was especially associated with increased risk among those reporting sleep problems or fatigue. These findings may help identify groups needing closer occupational health monitoring, though causal inference is limited by the observational design. Intervention studies are required to determine whether changes in work schedules or management of sleep problems and fatigue could reduce risk. by Shiri R, Vanttola P, Ervasti J, Koskinen A, Hansen J, Härmä M. doi:10.5271/sjweh.4289]]> Multiple maternal occupational exposures during pregnancy and newborn size at birth: analysis of the ELFE cohort, a French longitudinal study of children http://www.sjweh.fi/show_abstract.php?abstract_id=4289 http://www.sjweh.fi/show_abstract.php?abstract_id=4289 Thu, 14 May 2026 21:36:58 +0200 Original article 33 weeks). The outcomes of interest were SGA, BW, and HC. Of 47 factors (17 chemical, 8 physical, 4 biological, 12 biomechanical, 3 organizational and 3 psychosocial) to which mothers were exposed in their occupation assessed by job-exposure matrices in this cohort, we included those for which the epidemiological or experimental literature suggests an association with fetal growth. Logistic and linear regression models that included all preselected exposure variables were performed and adjusted for potential confounders. We conducted additional analysis stratified by trimester of pregnancy. Results The logistic model, which included all preselected variables, reported that – for all women – exposure to ultrafine particles (UFP) increased SGA risk [odds ratio (OR) 1.46, 95% confidence interval (CI) 1.12–1.90] while standing decreased it (OR 0.82, 95% CI 0.67–1.00). Among mothers who stopped working during the first/second trimester of pregnancy, we found the same SGA risk for UFP; exposure to high strain also increased the risk (OR 1.81, 95% CI 1.18–2.83). Among those who stopped working during the third trimester, exposure to oxygenated solvents increased SGA risk (OR 2.24, 95% CI 1.08–4.41). In the linear model, for all women, there was a decrease in BW (β -34 grams, 95% CI -66– -1.1) among those exposed to UFP. For mothers who stopped working during the first/second trimester, exposure to vibration increased BW, while among those who stopped working during the third trimester, exposure to night work increased BW. Exposure to oxygenated solvents decreased HC (β -0.22 cm, 95% CI -0.44–0.00) among all women. Conclusion These findings suggest the possible influence of chemical and strenuous factors at work on fetal growth, particularly depending on the trimester in which pregnant mothers stopped working. While the combined assessment of multiple exposures did not reveal clear associations, further studies are needed to explore potential interactions and underlying biological mechanisms. by Tartaglia M, Jaunas K, Audignon-Durand S, Houot M-T, Turuban M, Roeleveld N, Siemiatycki J, Dufourg MN, Carles C, Pilorget C, Uuksulainen S, Turner MC, Descatha A, Garlantézec R, Delva F. doi:10.5271/sjweh.4306]]> The moderating role of psychosocial work factors in the association between menopausal symptoms and work impairment http://www.sjweh.fi/show_abstract.php?abstract_id=4306 http://www.sjweh.fi/show_abstract.php?abstract_id=4306 Wed, 13 May 2026 11:14:17 +0200 Original article by Clevis MGA, van Oostrom SH, Loef B, MenoPause Consortium, van Valkengoed IGM, Nieuwenhuijsen K, Proper KI. doi:10.5271/sjweh.4307]]> Occupational exposure to carcinogenic substances in night versus day shift jobs http://www.sjweh.fi/show_abstract.php?abstract_id=4307 http://www.sjweh.fi/show_abstract.php?abstract_id=4307 Fri, 08 May 2026 12:22:07 +0200 Original article by Parks J, Zanif U, Bhatti P. doi:10.5271/sjweh.4305]]> Labor market participation among patients referred to occupational medicine with low-back pain: a Danish nationwide register-based cohort study http://www.sjweh.fi/show_abstract.php?abstract_id=4305 http://www.sjweh.fi/show_abstract.php?abstract_id=4305 Tue, 05 May 2026 12:36:26 +0200 Original article by Rønnow MM, Vestergaard JM, Rytter D, Fenger-Grøn M, Willert MV, Andersen JH, Kyndi M. doi:10.5271/sjweh.4294]]> Occupational heat stress and the role of wearable cooling interventions: A systematic review and meta-analysis of physiological and perceptual outcomes http://www.sjweh.fi/show_abstract.php?abstract_id=4294 http://www.sjweh.fi/show_abstract.php?abstract_id=4294 Thu, 30 Apr 2026 01:52:12 +0200 Review 2=43.91%], gastrointestinal temperature (MD -0.26°C; -0.52– -0.001; I2=98.13%), skin temperature (MD -1.14°C; -1.85– -0.42; I2=96.56%), and heart rate (MD -7.69 bpm; -11.22– -4.15; I2=73.19%). Egger’s tests suggested possible small-study effects for skin temperature and heart rate but not for core temperatures. Subgroup analyses indicated more consistent benefits with water/ice and PCM garments. Overall certainty ranged from low to very low due to risk of bias, inconsistency, and imprecision. Conclusions Wearable cooling attenuates physiological heat strain and improves thermal comfort, particularly via water/ice and PCM systems. Given high heterogeneity and low certainty, adequately powered, standardized, head-to-head trials are needed. by Sheth A, Viramgami A, Thakor M, Modi B, Bagepally B, Kar A, Ram E, Dave A, Balachandar R. doi:10.5271/sjweh.4302]]> Onset of workplace bullying and violence and changes in health-related behaviors: a multi-cohort study http://www.sjweh.fi/show_abstract.php?abstract_id=4302 http://www.sjweh.fi/show_abstract.php?abstract_id=4302 Thu, 30 Apr 2026 01:22:23 +0200 Original article X and TX+1 (concurrent analysis). To clarify temporality, changes in health-related behaviors were further calculated at time TX+1 to TX+2 (longitudinal analysis). We applied logistic regression with generalized estimating equations. Subgroup differences by sex were examined. Results Among 125 854 participant-observations across 2–3 study phases of the 78 624 participants, 6–8% experienced onset of workplace bullying and 9–14% reported onset of workplace violence over 1–2 years. The strongest association was observed between onset of violence and becoming obese, with an odds ratio (OR) of 1.13 [95% confidence interval (CI) 1.00–1.27] in the concurrent and 1.31 (95% CI 1.05–1.64) in the longitudinal analysis. In addition, onset of bullying (OR 1.23, 95% CI 1.06–1.44) and violence (OR 1.11, 95% CI 0.99–1.24) were concurrently associated with initiation of excessive alcohol use, with weaker associations in the longitudinal analysis. Exposure–response relationships were observed for all aforementioned associations and findings were consistent across cohorts. Men were more likely to initiate excessive alcohol use than women after experiencing violence (P=0.008). Conclusion Exposure to workplace bullying and violence was associated with adverse changes in health-related behaviors. by Xu T, Nielsen MB, Clark AJ, Rugulies R, Pentti J, Sørensen JK, Nordentoft M, Westerlund H, Stenholm S, Vahtera J, Madsen IEH, Hansen ÅM, Virtanen M, Knardahl S, Oksanen T, Kivimäki M, Magnusson Hanson LL, Rod NH. doi:10.5271/sjweh.4303]]> The consequences of changes in exercise habits on work engagement and presenteeism: Evidence from an event-study analysis using Japanese longitudinal data http://www.sjweh.fi/show_abstract.php?abstract_id=4303 http://www.sjweh.fi/show_abstract.php?abstract_id=4303 Thu, 30 Apr 2026 00:07:54 +0200 Original article by Kashima R, Takada T, Matsuo T, So R. doi:10.5271/sjweh.4297]]> Workplace mistreatment and problem drinking among physicians in Sweden: a longitudinal study http://www.sjweh.fi/show_abstract.php?abstract_id=4297 http://www.sjweh.fi/show_abstract.php?abstract_id=4297 Mon, 20 Apr 2026 17:46:58 +0200 Original article by Peláez Zuberbuhler J, Strömberg A, Thern E, Landstad BJ, Sjöström M, Brulin E. doi:10.5271/sjweh.4299]]> The demands–control–support work stress model and risk of ischemic heart disease: causal inference based on observational epidemiology http://www.sjweh.fi/show_abstract.php?abstract_id=4299 http://www.sjweh.fi/show_abstract.php?abstract_id=4299 Fri, 17 Apr 2026 16:49:24 +0200 Review by Bonde JP, Skaaby S, Flachs EM, Dollard M, Keyes K, Rosengren A, Mehlum IS, Mikkelsen S. doi:10.5271/sjweh.4291]]> Permanent night work and risk of injuries: A register-based cohort study using payroll data http://www.sjweh.fi/show_abstract.php?abstract_id=4291 http://www.sjweh.fi/show_abstract.php?abstract_id=4291 Wed, 15 Apr 2026 15:49:12 +0200 Original article by Nabe-Nielsen K, Aagaard A, Larsen AD, Nielsen HB, Hansen J, Hansen ÅM, Kolstad HA, Vestergaard JM, Garde AH. doi:10.5271/sjweh.4295]]> Adaptation across consecutive night shifts at 71°N under Arctic summer daylight and winter darkness: Effects on alertness, sleepiness, and fatigue http://www.sjweh.fi/show_abstract.php?abstract_id=4295 http://www.sjweh.fi/show_abstract.php?abstract_id=4295 Fri, 10 Apr 2026 00:23:00 +0200 Original article by Holme AN, Moen LV, Sallinen M, Nilsen KB, Boccara CN, Phillips AJK, Haugen F, Matre D. doi:10.5271/sjweh.4290]]> Night shift work and risk of total and site-specific cancer: results from a prospective cohort study among Chinese men http://www.sjweh.fi/show_abstract.php?abstract_id=4290 http://www.sjweh.fi/show_abstract.php?abstract_id=4290 Thu, 09 Apr 2026 23:35:32 +0200 Original article by Shen Q-M, Li Z-Y, Tan Y-T, Gao L-F, Liu D-K, Li H-L, Yang W-S, Xiang Y-B. doi:10.5271/sjweh.4300]]> Health and working careers of informal carers – what we know and do not yet (but should) know http://www.sjweh.fi/show_abstract.php?abstract_id=4300 http://www.sjweh.fi/show_abstract.php?abstract_id=4300 Wed, 08 Apr 2026 11:52:17 +0200 Editorial References 1. 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Health effects of informal caregiving across Europe: A longitudinal approach. Soc Sci Med. 2017;173:72-80. https://doi.org/10.1016/j.socscimed.2016.11.036 6. Mikkola TM, Mänty M, Kautiainen H, von Bonsdorff MB, Haanpää M, Koponen H, et al. Work incapacity among family caregivers: a record linkage study. J Epidemiol Community Health. 2022;76(6):580-5. https://doi.org/10.1136/jech-2021-217901 7. Lacey RE, Xue B, Di Gessa G, Lu W, McMunn A. Mental and physical health changes around transitions into unpaid caregiving in the UK: a longitudinal, propensity score analysis. Lancet Pub Health. 2024;9(1):e16-e25. https://doi.org/10.1016/S2468-2667(23)00206-2 8. Lee S, Colditz GA, Berkman LF, Kawachi I. Caregiving and risk of coronary heart disease in U.S. women: a prospective study. Am J Prev Med. 2003;24(2):113-9. https://doi.org/10.1016/S0749-3797(02)00582-2 9. Park SS. Caregivers’ Mental Health and Somatic Symptoms During COVID-19. 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Scand J Work Environ Health. 2017;43(5):426-35. https://doi.org/10.5271/sjweh.3645 by Ervasti J, Mikkola TM. doi:10.5271/sjweh.4292]]> From secondary special needs education to the labor market: latent trajectories and inequalities in employment participation http://www.sjweh.fi/show_abstract.php?abstract_id=4292 http://www.sjweh.fi/show_abstract.php?abstract_id=4292 Mon, 06 Apr 2026 16:25:03 +0200 Original article by Ciliacus R, Porru F, Burdorf A, Schuring M. doi:10.5271/sjweh.4285]]> Evaluating a new voluntary occupational health and safety management system program in the context of a pandemic http://www.sjweh.fi/show_abstract.php?abstract_id=4285 http://www.sjweh.fi/show_abstract.php?abstract_id=4285 Thu, 02 Apr 2026 15:22:20 +0200 Original article by Sivaraj LB, Macpherson RA, McLeod CB. doi:10.5271/sjweh.4282]]> Adverse occupational outcome among workers with occupational asthma: A systematic review and meta-analysis of influencing factors http://www.sjweh.fi/show_abstract.php?abstract_id=4282 http://www.sjweh.fi/show_abstract.php?abstract_id=4282 Thu, 02 Apr 2026 12:27:16 +0200 Review 2=86.0%; 95% PI 10.2–73.4). Prevalence of AOO varied by: (i) data sources (registry/compensation: 50.1% versus clinic: 32.0%; P=0.015); (ii) study size (>80 participants: 43.4% versus ≤80: 27.9%; P=0.033); (iii) baseline forced expiratory volume in 1 second (FEV1) (≤85% predicted: 38.2% versus >85% predicted: 13.8%; P=0.008); and (iv) exposure duration before symptom onset (>7.1 years: 35.7% versus ≤7.1 years: 15.7%; P=0.015). Heterogeneity across studies was substantial and several subgroups included fewer than five studies. Conclusions More than one-third of workers with OA experience an AOO. The findings highlight the need for harmonized outcome definitions and for interventions integrating early referral, exposure control, and structured return-to-work programs to avoid AOO. by Damerau LS, Helm MW, Pieter J, Velasco Garrido M, Harth V, Hoven H, Preisser AM. doi:10.5271/sjweh.4280]]> Occupational exposure limits for psychosocial hazards: A promising concept or a premature leap? http://www.sjweh.fi/show_abstract.php?abstract_id=4280 http://www.sjweh.fi/show_abstract.php?abstract_id=4280 Mon, 02 Mar 2026 13:24:50 +0200 Commentary by Guseva Canu I, van der Molen HF]]>