PT Journal AU Kanerva, L Jolanki, R Tupasela, O Halmepuro, L Keskinen, H Estlander, T Sysilampi, ML TI Immediate and delayed allergy from epoxy resins based on diglycidyl ether of bisphenol A. SO Scandinavian Journal of Work, Environment & Health PD 6VL PY 1991 BP 208 EP 215 IS 3 DI 10.5271/sjweh.1718 WP https://www.sjweh.fi/show_abstract.php?abstract_id=1718 SN 0355-3140 AB

This case report presents two patients with immediate and delayed allergy to epoxy resins based on diglycidyl ether of bisphenol A (DGEBA). In patch testing, the epoxy resin (DGEBA-based) of the standard series gave allergic reactions. Both patients had a prick test reaction of histamine size or larger to the human serum albumin (HSA) conjugate of DGEBA-based epoxy resins. One had been occupationally exposed to methyl tetrahydrophthalic anhydride (MTHPA) and had a histamine-size prick test reaction to the HSA conjugate of MTHPA; the other did not react to the conjugate. Determinations of specific immunoglobulin E were carried out with HSA-DGEBA conjugates, two DGEBA-based epoxy resins, and phthalic anhydrides. The first patient had positive tests to DGEBA, the DGEBA-based epoxy resins, and two phthalic anhydrides, and the second to DGEBA and the DGEBA-based epoxy resins, but not to the phthalic anhydrides.

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