PT Journal AU Jarup, L Rogenfelt, A Elinder, CG Nogawa, K Kjellstrom, T TI Biological half-time of cadmium in the blood of workers after cessation of exposure. SO Scandinavian Journal of Work, Environment & Health PD 8VL PY 1983 BP 327 EP 331 IS 4 DI 10.5271/sjweh.2404 WP https://www.sjweh.fi/show_abstract.php?abstract_id=2404 SN 0355-3140 AB

The biological half-time of cadmium in the blood of previously exposed workers was estimated after the cessation of exposure. Five men were followed for a period of 10 to 13 years. One-compartment and two-compartment exponential elimination models were used to describe the decrease in blood cadmium levels over time. The best fit to the observed data was obtained with a two-compartment model. The half-times estimated from this model ranged from 75 to 128 d for the fast component and from 7.4 to 16.0 years for the slow component. The results confirm that there is a very long whole-body biological half-time for cadmium, and the estimated half-times are similar to those obtained with different methods.

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