PT Journal AU Hogstedt, B Akesson, B Axell, K Gullberg, B Mitelman, F Pero, RW Skerfving, S Welinder, H TI Increased frequency of lymphocyte micronuclei in workers producing reinforced polyester resin with low exposure to styrene. SO Scandinavian Journal of Work, Environment & Health PD 6VL PY 1983 BP 241 EP 246 IS 3 DI 10.5271/sjweh.2414 WP https://www.sjweh.fi/show_abstract.php?abstract_id=2414 SN 0355-3140 AB

A new micronucleus method based on the analysis of lymphocytes with preserved cytoplasm revealed an increased frequency of micronuclei in 38 workers employed in a plant producing styrene-modified polyester resin as compared to the frequency in 20 referents (5.9 vs 3.6%). The time-weighted average of the styrene concentration in the workroom air varied between 1 and 36 ppm (mean 13 ppm) during the last year and correlated well to low urinary levels of mandelic acid, which ranged from 9 to 316 mg/g of creatinine (mean 65 mg/g of creatinine).

ER