TY - JOUR T1 - Human response to controlled levels of combinations of sulfur dioxide and inert dust. JO - Scandinavian Journal of Work, Environment & Health PY - 1981/3VL - 7 IS - 1 SP - 1 EP - 7 AU - Andersen, Ingelise AU - Mølhave, Lars AU - Proctor, Donald F M3 - doi: 10.5271/sjweh.2570 UR - https://www.sjweh.fi/show_abstract.php?abstract_id=2570 KW - airway resistance KW - combination KW - controlled level KW - discomfort KW - environmental chamber KW - human response KW - inert dust KW - mucociliary clearance KW - nose KW - particle KW - rhinomanometry KW - sulfur dioxide KW - vanadium KW - workroom air N2 -

Under controlled conditions in an environmental chamber 16 healthy young volunteers were exposed to combinations of sulfur dioxide (SO2) (2.6 or 13 mg/m3) and inert plastic dust (2 or 10 mg/m3) or of SO2 (13 mg/m3) and dust (10 mg/m3) coated with vanadium. During periods of clean air and during exposures of 5-h duration nasal mucus flow rate, nasal airflow resistance, forced vital capacity, and subjective discomfort were measured. Reductions in nasal mucus flow rate, forced expiratory flow (FEF25-75%), and discomfort were related principally to the SO2 concentration. The combined effects of SO2 and dust were, at the most, additive, and there was no indication of potentiation effects. No effect could be attributed to the coating of the dust with vanadium.

SN - 0355-3140 ER -