TY - JOUR T1 - Biologically active metals in human tissues. I. The effect of age and sex on the concentration of copper in aorta, heart, kidney, liver, lung, pancreas and skeletal muscle. JO - Scandinavian Journal of Work, Environment & Health PY - 1978/6VL - 4 IS - 2 SP - 167 EP - 175 AU - Vuori, Erkki AU - Huunan-Seppälä, Antti AU - Kilpiö, Jukka O M3 - doi: 10.5271/sjweh.2712 UR - https://www.sjweh.fi/show_abstract.php?abstract_id=2712 KW - age KW - aorta KW - biologically active metal KW - concentration of copper KW - copper KW - heart KW - human tissue KW - kidney KW - liver KW - lung KW - pancreas KW - sex KW - skeletal muscle N2 -

Autopsy specimens of aorta, heart, kidney, liver, lung, pancreas and skeletal muscle were collected from 86 accident victims. The copper concentration in each tissue was determined with atomic absorption spectrophotometry. The descending order of the tissues in respect to copper concentration was: liver, heart, kidney, pancreas, lung, muscle, and aorta. No significant difference was found in the copper levels of samples from male and female autopsies. When the effect of age on the average copper concentration was studied, liver and kidney showed a decreasing concentration up to maturity, the copper concentration in pancreas and skeletal muscle showed a continuous decline with increasing age, and there was no clear-cut effect of age on the copper concentration of heart, lung and aorta. According to the results the Finnish population does not differ, on the average, from other populations with respect to tissue copper concentrations.

SN - 0355-3140 ER -