PT Journal AU Pagano, G Esposito, A Giordano, GG Hagström, BE TI Embryotoxic and teratogenic effects of styrene derivatives on sea urchin development. SO Scandinavian Journal of Work, Environment & Health PD VL PY 1978 BP 136 EP 141 IS 2 DI 10.5271/sjweh.2753 WP https://www.sjweh.fi/show_abstract.php?abstract_id=2753 DE development; embryotoxic effect; fertilization; mutagenicity; sea urchin; sea urchin development; styrene; styrene derivative; teratogenic effect SN 0355-3140 AB

The effects of styrene and some of its derivatives on the fertilization and differentiation of sea urchins was investigated. When one of the gametes was pretreated for a few minutes, it was ascertained that the test substances act on the haploid nucleus, producing specific changes in the differentiation of the embryo. By this test system directly acting, weak mutagens may be detected.

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