PT Journal AU Holtermann, A Mortensen, OS Burr, H Søgaard, K Gyntelberg, F Suadicani, P TI Fitness, work, and leisure-time physical activity and ischaemic heart disease and all-cause mortality among men with pre-existing cardiovascular disease SO Scandinavian Journal of Work, Environment & Health PD 9VL PY 2010 BP 366 EP 372 IS 5 DI 10.5271/sjweh.2914 WP https://www.sjweh.fi/show_abstract.php?abstract_id=2914 DE all-cause mortality; cardiovascular disease; cardiovascular health; fitness; health; ischaemic heart disease; leisure-time; leisure-time physical activity; man; men; mortality; occupational health; occupational physical activity; physical activity; physical fitness; work SN 0355-3140 AB '

'

OBJECTIVE ': 'Our aim was to study the relative impact of physical fitness, physical demands at work, and physical activity during leisure time on ischaemic heart disease (IHD) and all-cause mortality among employed men with pre-existing cardiovascular disease (CVD).

'

'

METHOD ': 'We carried out a 30-year follow-up of the Copenhagen Male Study of 274 gainfully employed men, aged 40–59 years who had a history of CVD (ie, myocardial infarction, angina pectoris, and intermittent claudication). We estimated physical fitness [maximal oxygen consumption (VO2Max)] using the Åstrand cycling test and determined physical work demands and leisure-time physical activity using a self-reported questionnaire. Results Among 274 men with a history of CVD, 93 men died from IHD. Using male employees with a history of CVD and a low level of fitness as the reference group, our Cox analyses – adjusted for age, blood pressure, smoking, alcohol consumption, body mass index, diabetes, hypertension, physical work demands, leisure-time physical activity, and social class – showed a substantially reduced risk for IHD mortality among employees who were intermediately fit [VO2Max range 25–36; hazard ratio (HR) 0.54, 95% confidence interval (95% CI) CI 0.32–0.93] and highly fit (VO2Max range 37–50; HR 0.28, 95% CI 0.12–0.66). We found a positive, but statistically non-significant association between physical demands at work and all-cause mortality.

'

'

CONCLUSION ': 'Among gainfully employed men with pre-existing CVD, a high physical fitness was associated with a substantially reduced risk for IHD and all-cause mortality.

ER