@Article{Burch1998, author = "Burch, J. B. and Reif, John S. and Yost, M. G. and Keefe, T. J. and Pitrat, C. A.", title = "Nocturnal excretion of a urinary melatonin metabolite among electric utility workers", journal = "Scandinavian Journal of Work, Environment & Health", year = "1998", month = "Jun", day = "24", number = "3", pages = "183--189", keywords = "6-hydroxymelatonin sulfate; electromagnetic fields; human; magnetic fields; pineal", abstract = "'
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OBJECTIVES ': 'The effects of 60-Hz magnetic field and ambient light exposures on the pineal hormone melatonin were studied among electric utility workers.'
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METHODS ': 'Personal exposure was measured at 15-second intervals over 3 consecutive 24-hour periods. Exposure metrics based on magnetic field intensity, intermittence, or temporal stability were calculated for periods of work, home, and sleep. A rate-of-change metric (RCM) was used to estimate intermittence, and the standardized RCM (RCMS = RCM/standard deviation) was used to evaluate temporal stability. The effects of magnetic field exposure on total overnight 6-hydroxymelatonin sulfate (6-OHMS) excretion and creatinine-adjusted nocturnal 6-OHMS (6-OHMS/cr) concentration were analyzed with adjustment for age, month, and light exposure.'
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RESULTS ': 'Magnetic field intensity, intermittence, or cumulative exposure had little influence on nocturnal 6-OHMS excretion. Residential RCMS magnetic field exposures were associated with lower nocturnal 6-OHMS/cr concentrations. In multivariate statistical analyses, the interaction term for geometric mean and RCMS magnetic field exposures at home was associated with lower nocturnal 6-OHMS/cr and overnight 6-OHMS levels. Modest reductions in the mean 6-OHMS levels occurred after RCMS exposures during work. The greatest reductions occurred when RCMS exposures both at work and at home were combined; therefore the effects of temporally stable magnetic fields may be integrated over a large portion of the day.'
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CONCLUSION ': 'Results from this study provide evidence that temporally stable magnetic field exposures are associated with reduced nocturnal 6-OHMS excretion in humans.
", issn = "0355-3140", doi = "10.5271/sjweh.297", url = "https://www.sjweh.fi/show_abstract.php?abstract_id=297", url = "https://doi.org/10.5271/sjweh.297" }