TY - JOUR T1 - Meta-analyses of non-Hodgkin's lymphoma and farming JO - Scandinavian Journal of Work, Environment & Health PY - 1998/8VL - 24 IS - 4 SP - 255 EP - 261 AU - Khuder, SA AU - Schaub, EA AU - Keller-Byrne, JE M3 - doi: 10.5271/sjweh.318 UR - https://www.sjweh.fi/show_abstract.php?abstract_id=318 KW - farmer KW - infection KW - pesticide N2 - '

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OBJECTIVES ': 'This study examined the association between non-Hodgkin's lymphoma (NHL) and farming.'

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METHODS ': 'A series of meta-analyses of peer-reviewed studies was performed using 36 studies published between 1982 and 1997. Prior to the meta-analyses, all the studies were reviewed and evaluated for heterogeneity and publication bias. Combined relative risks (RR) were calculated using the random effect model.'

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RESULTS ': 'The combined RR was 1.10 [95% confidence interval (95% CI) 1.03-1.19] for all the studies and 0.93 (95% CI 0.82-1.06) for studies involving female farmers. Significant heterogeneity was detected for study design and country of study among the studies. Significantly elevated RR values were obtained for case-referent studies (combined RR 1.19, 95% CI 1.06-1.33) and for studies conducted on farmers residing in the United States (combined RR 1.26, 95% CI 1.15-1.37). These findings were not influenced by a publication bias.'

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CONCLUSION ': 'The findings suggest that male farmers residing in the United States have a slightly elevated risk of contracting NHL. Commonly experienced exposures that might contribute to the occurrence of NHL in this group include infectious microorganisms, herbicides, and insecticides.

SN - 0355-3140 ER -