TY - JOUR T1 - Exposure to psychosocial job strain during pregnancy and odds of asthma and atopic dermatitis among 7-year old children – a prospective cohort study JO - Scandinavian Journal of Work, Environment & Health PY - 2014/11VL - 40 IS - 6 SP - 639 EP - 648 AU - Larsen, Ann Dyreborg AU - Schlünssen, Vivi AU - Christensen, Berit Hvass AU - Bonde, Jens Peter AU - Obel, Carsten AU - Thulstrup, Ane Marie AU - Hannerz, Harald AU - Hougaard, Karin Sørig M3 - doi: 10.5271/sjweh.3452 UR - https://www.sjweh.fi/show_abstract.php?abstract_id=3452 KW - allergic disease KW - asthma KW - atopic dermatitis KW - birth cohort KW - children KW - Danish National Birth Cohort KW - exposure KW - high demand KW - job control KW - job demand KW - job strain KW - low control KW - offspring KW - pregnancy KW - prenatal stress KW - psychosocial KW - psychosocial job strain N2 - '

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OBJECTIVES ': 'Few epidemiological studies have studied maternal stress exposure during pregnancy and odds of asthma and atopic dermatitis (AD) among offspring, and none have extended the focus to psychosocial job strain. The aim of this study was to assess the association between maternal job strain during pregnancy and asthma as well as AD among 7-year-old children.

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METHODS ': 'The study is based on the Danish National Birth Cohort and includes prospective data from 32 104 pregnancies. Job strain was assessed early in pregnancy by use of two questions on demands and control. We categorized participants into four job strain categories: low strain (low demands, high control), active (high demands, high control), passive (low demands, low control), and high strain (high demands, low control). Information on asthma and AD until age seven was collected using maternal self-report. Multinomial logistic regression models were used to estimate odds ratios (OR) with 95% confidence intervals (95% CI) adjusted for several covariates.

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RESULTS ': 'Maternal exposure to self-reported high strain during pregnancy was associated with 15% higher odds of atopic dermatitis among 7-year-old children (ORadj 1.15, 95% CI 1.02–1.31). Furthermore, an association between the active jobs and asthma among 7-year-old children was found (ORadj 1.13, 95% CI 1.03–1.24).

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CONCLUSION ': 'Maternal exposure to high strain and active jobs during pregnancy was associated with asthma and atopic dermatitis among 7-year-old children.

SN - 0355-3140 ER -