@Article{Taeger2015, author = "Taeger, Dirk and Pesch, Beate and Kendzia, Benjamin and Behrens, Thomas and Jöckel, Karl-Heinz and Dahmann, Dirk and Siemiatycki, Jack and Kromhout, Hans and Vermeulen, Roel and Peters, Susan and Olsson, Ann and Brüske, Irene and Wichmann, Heinz-Erich and Stücker, Isabelle and Guida, Florence and Tardón, Adonina and Merletti, Franco and Mirabelli, Dario and Richiardi, Lorenzo and Pohlabeln, Hermann and Ahrens, Wolfgang and Landi, Maria Teresa and Caporaso, Neil and Pesatori, Angela Cecilia and Mukeriya, Anush and Szeszenia-Dabrowska, Neonila and Lissowska, Jolanta and Gustavsson, Per and Field, John and Marcus, Michael W. and Fabianova, Eleonora and ’t Mannetje, Andrea and Pearce, Neil and Rudnai, Peter and Bencko, Vladimir and Janout, Vladimir and Dumitru, Rodica Stanescu and Foretova, Lenka and Forastiere, Francesco and McLaughlin, John and Demers, Paul and Bueno-de-Mesquita, Bas and Schüz, Joachim and Straif, Kurt and Brüning, Thomas", title = "Lung cancer among coal miners, ore miners and quarrymen: smoking-adjusted risk estimates from the synergy pooled analysis of case–control studies", journal = "Scandinavian Journal of Work, Environment & Health", year = "2015", month = "Sep", day = "41", number = "5", pages = "467--477", keywords = "cancer; case–control study; coal miner; coal mining; histological subtype; lung cancer; mining; ore miner; ore mining; pooled analysis; population-based study; quarrymen; risk estimate; smoking", abstract = "'
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OBJECTIVES ': 'Working in mines and quarries has been associated with an elevated lung cancer risk but with inconsistent results for coal miners. This study aimed to estimate the smoking-adjusted lung cancer risk among coal miners and compare the risk pattern with lung cancer risks among ore miners and quarrymen.
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METHODS ': 'We estimated lung cancer risks of coal and ore miners and quarrymen among 14 251 lung cancer cases and 17 267 controls from the SYNERGY pooled case–control study, controlling for smoking and employment in other at-risk occupations.
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RESULTS ': 'Ever working as miner or quarryman (690 cases, 436 controls) was associated with an elevated odds ratio (OR) of 1.55 [95% confidence interval (95% CI) 1.34–1.79] for lung cancer. Ore miners (53 cases, 24 controls) had a higher OR (2.34, 95% CI 1.36-4.03) than quarrymen (67 cases, 39 controls; OR 1.92, 95% CI 1.21–3.05) and coal miners (442 cases, 297 controls; OR 1.40, 95% CI 1.18–1.67), but CI overlapped. We did not observe trends by duration of exposure or time since last exposure.
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CONCLUSIONS ': 'This pooled analysis of population-based studies demonstrated an excess lung cancer risk among miners and quarrymen that remained increased after adjustment for detailed smoking history and working in other at-risk occupations. The increase in risk among coal miners were less pronounced than for ore miners or quarrymen.
", issn = "0355-3140", doi = "10.5271/sjweh.3513", url = "https://www.sjweh.fi/show_abstract.php?abstract_id=3513", url = "https://doi.org/10.5271/sjweh.3513" }