%0 Journal Article %T Job strain and effort-reward imbalance as risk factors for type 2 diabetes mellitus: A systematic review and meta-analysis of prospective studies %A Pena-Gralle, Ana Paula B. %A Talbot, Denis %A Duchaine, Caroline S. %A Lavigne-Robichaud, Mathilde %A Trudel, Xavier %A Aubé, Karine %A Gralle, Matthias %A Gilbert-Ouimet, Mahée %A Milot, Alain %A Brisson, Chantal %J Scandinavian Journal of Work, Environment & Health %D 2022 %8 January 48 %N 1 %@ 0355-3140 %F Pena-Gralle2022 %X '

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OBJECTIVES ': 'This systematic review and meta-analysis aimed to synthesize the available data on prospective associations between work-related stressors and the risk of type 2 diabetes mellitus (T2DM) among adult workers, according to the demand–control–support (DCS) and the effort–reward imbalance (ERI) models.

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METHOD ': 'We searched for prospective studies in PubMed, EMBASE, Web of Science, Scopus, CINHAL and PsychInfo. After screening and extraction, quality of evidence was assessed using the ROBINS-I tool adapted for observational studies. The effect estimates extracted for each cohort were synthesized using random effect models.

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RESULTS ': 'We included 18 studies (reporting data on 25 cohorts) in meta-analyses for job strain, job demands, job control, social support at work and ERI. Workers exposed to job strain had a higher risk of developing T2DM when compared to unexposed workers [pooled rate ratio (RR) 1.16, 95% confidence interval (CI) 1.07–1.26]. This association was robust in several supplementary analyses. For exposed women relative to unexposed women, the RR was 1.35 (95% CI 1.12–1.64). The RR of workers exposed to ERI was 1.24 (95% CI 1.08–1.42) compared to unexposed workers.

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CONCLUSIONS ': 'This is the first meta-analysis to find an effect of ERI on the onset of T2DM incidence. It also confirms that job strain increases the incidence of T2DM, especially among women.

%K adult-onset diabetes %K cohort study %K demand–control %K diabetes %K diabetes mellitus %K effort–reward imbalance %K ERI %K job strain %K risk factor %K ROBINS-I %K type 2 diabetes %K work stress %R 10.5271/sjweh.3987 %U https://www.sjweh.fi/show_abstract.php?abstract_id=3987 %U https://doi.org/10.5271/sjweh.3987 %P 5-20