TY - JOUR T1 - Shift work, risk factors and cardiovascular disease JO - Scandinavian Journal of Work, Environment & Health PY - 1999/4VL - 25 IS - 2 SP - 85 EP - 99 AU - Bøggild, Henrik AU - Knutsson, Anders M3 - doi: 10.5271/sjweh.410 UR - https://www.sjweh.fi/show_abstract.php?abstract_id=410 KW - cardiovascular disease epidemiology KW - review KW - risk factor KW - work schedule N2 -

The literature on shift work, morbidity and mortality from cardiovascular disease, and changes in traditional risk factors is reviewed. Seventeen studies have dealt with shift work and cardiovascular disease risk. On balance, shift workers were found to have a 40% increase in risk. Causal mechanisms of this risk via known cardiovascular risk factors, in relation to circadian rhythms, disturbed sociotemporal patterns, social support, stress, behavior (smoking, diet, alcohol, exercise), and biochemical changes (cholesterol, triglycerides, etc) are discussed. The risk is probably multifactorial, but the literature has focused on the behavior of shift workers and has neglected other possible causal connections. In most studies methodological problems are present; these problems are related to selection bias, exposure classification, outcome classification, and the appropriateness of comparison groups. Suggestions for the direction of future research on this topic are proposed.

SN - 0355-3140 ER -