@Article{Aaserud2000, author = "Aaserud, O. and Nakstad, P. H. and Bakke, S. J. and Reinvang, I. and Borchgrevink, H. M. and Lie, V. and Malt, U. F. and Gjerstad, L.", title = "Failure to confi rm neurotoxic impairment using cerebral magnetic resonance imaging on solvent-exposed workers", journal = "Scandinavian Journal of Work, Environment & Health", year = "2000", month = "Aug", day = "26", number = "4", pages = "346--352", keywords = "basal ganglia; brain dysfunction; cerebral atrophy; occupational exposure; organic solvent", abstract = "'
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OBJECTIVES ': 'The study aimed at assessing signs of nervous system impairment by cerebral magnetic resonance imaging (MRI) among workers with a history of long-term exposure to mixtures of organic solvents.'
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METHODS ': 'Thirty-six workers (mean age 44.1 years) with at least 10 (mean 23.9) years of occupational exposure to solvents and pair-matched referents with no former solvent exposure went through a blind, random-order investigation of cerebral MRI, performed with a 1.5-tesla scanner.'
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RESULTS ': 'Linear measurements of the MRI tomograms showed a slight tendency toward wider ventricles and broader cortical sulci in the reference group. Visual evaluation of the MRI by 2 experienced neuroradiologists showed no significant difference between the groups; however, there was substantial interobserver variability.'
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CONCLUSIONS ': 'The MRI findings of this study do not support the hypothesis that long-term low-level occupational exposure to organic solvents results in the development of brain atrophy, or specific MRI signal changes in the region of the basal ganglia and thalami.
", issn = "0355-3140", doi = "10.5271/sjweh.552", url = "https://www.sjweh.fi/show_abstract.php?abstract_id=552", url = "https://doi.org/10.5271/sjweh.552" }