PT Journal AU Hengstler, JG Fuchs, J Bolm-Audorff, U Meyer, S Oesch, F TI Single-strand breaks in deoxyribonucleic acid in fire fighters accidentally exposed to o-nitroanisole and other chemicals SO Scandinavian Journal of Work, Environment & Health PD 2VL PY 1995 BP 36 EP 42 IS 1 DI 10.5271/sjweh.6 WP https://www.sjweh.fi/show_abstract.php?abstract_id=6 DE acute toxicity; biomonitoring; dna single-strand breaks; fire fighter; human mononuclear blood cells; o-nitroanisole SN 0355-3140 AB '

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OBJECTIVES ': 'The aim of the study was to detect single-strand breaks in deoxyribonucleic acid (DNA) in mononuclear blood cells of fire fighters exposed to o-nitroanisole and other substances released into the environment during an accident in a chemical plant.'

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METHODS ': 'The level of DNA single-strand breaks in mononuclear blood cells was detected by alkaline elution. The results for 16 fire fighters who worked in a contaminated area for about 8 h and two references groups (one of fire fighters who had not worked in the contaminated area and one of persons without any apparent occupational exposure to genotoxic substances).'

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RESULTS ': 'The mean normalized elution rate (nER) 19 d after the accident was slightly but statistically significantly (P ER