Scand J Work Environ Health 1978;4 suppl 2:181-183    pdf


Neurotoxicity of styrene in occupational and experimental exposure.

by Seppäläinen AM

Occupational styrene exposure caused an increased frequency of abnormal electroencephalograms which correlated to degree of exposure. No dose-response relationship could be shown concerning a slowing of nerve conduction velocities in workers exposed to styrene. Experimental exposure of rats to 300 ppm of styrene caused a transient increase in the nerve conduction velocity in 6 weeks, but in a comparison to control rats no difference was found in measurements performed on rats exposed for 8 and 11 weeks.