OBJECTIVES: Blood lead concentrations in a Danish reference population were related to information from an extensive questionnaire on work, environment, and life-style. METHODS: Data were gathered for 209 persons by means of a questionnaire and blood lead analyses. RESULTS: The mean concentration of lead in blood was 0.167 µmol/l (ie, significantly lower than in previous studies). This finding is in accordance with the fact that less than 10% of the gasoline used in Denmark contains lead additives (up to 0.15 g/l). An important finding was that the well-documented predictors for lead in blood at higher concentration levels, such as age, gender, menopausal status, and intake of alcohol, are still valid in a low-level exposure situation. In addition, a strong and negative correlation was found between blood lead concentrations and dietary supplementation with vitamins and minerals. CONCLUSION: The present data indicate that lead exposure may still constitute a health risk in a small proportion of adult men and postmenopausal women.