Case report

Scand J Work Environ Health 2000;26(1):78-80    pdf

doi:10.5271/sjweh.514

Late asthmatic reaction caused by naphthylene-1,5 diisocyanate

by Baur X, Wieners D, Marczynski B

After occupational exposure to napthylene-1,5 diisocyanate (NDI) for 2 years, a 33-year-old female worker developed work-related asthma attacks. Occupational-type exposure tests with NDI resulted in a late asthmatic response, whereas a corresponding challenge test with 4,4'-methylenediphenyl diisocyanate was negative. We conclude that NDI exposure in the range of its occupational exposure limit caused occupational asthma in this subject.