Scand J Work Environ Health 2003;29(6):411-430    pdf


Eye irritation and environmental factors in the office environment-hypotheses, causes and a physiological model

by Wolkoff P, Skov P, Franck C, Petersen LN

The study reviews eye irritation using a multidisciplinary approach. Potential risk factors and objective gender differences are identified, and possible hypotheses for eye irritation caused by indoor air pollution are discussed. Eye irritation depends somewhat on destabilization of the outer-eye tear film. An integrated physiological risk model with blink frequency, destabilization, and break-up of the eye tear film as inseparable phenomena may explain eye irritation among office workers in terms of occupational, climate, and eye-related physiological risk factors. Certain volatile organic compounds that are both chemically reactive and airway irritants may cause eye irritation. If airborne particles alone should destabilize the tear film and cause eye irritation, their content of surface-active compounds must be high. Personal factors (eg, use of contact lenses, eye make-up, and certain medication) may also affect destabilization of the eye tear film and possibly result in more eye symptoms.

This article refers to the following texts of the Journal: 1999;25(5):442-449  2000;26(6):514-522
The following article refers to this text: 2003;29(6):407-410