Proceedings paper

Scand J Work Environ Health 1995;21 suppl 2:99-103    pdf

Cancer risk assessment for crystalline silica to implement California's Hot Spots Act

by Collins JF, Marty MA

Crystalline silica has been identified as a probable human carcinogen. To assess the potential for adverse health effects due to environmental exposures to respirable crystalline silica, a quantitative estimate of carcinogenicity has been made using incidence data from three studies in which long-term silica inhalation caused lung tumors in rats. The uncertainties in risk assessment in general and in the risk assessment for silica in particular are discussed.