Original article

Scand J Work Environ Health 2019;45(6):577-587    pdf full text

https://doi.org/10.5271/sjweh.3831 | Published online: 24 May 2019, Issue date: 01 Nov 2019

Night work and postpartum depression: a national register-based cohort study

by Hammer P, Hageman I, Garde A, Begtrup L, Flachs E, Hansen J, Hansen Å, Hougaard K, Kolstad H, Larsen A, Pinborg A, Specht I, Bonde JP

Objective We aimed to investigate the association of night work during pregnancy with the risk of severe postpartum depression (PPD).

Methods We performed a nationwide register-based cohort study of workers in all Danish public hospitals. Daily information on working hours was retrieved from the Danish Working Hour Database from January 2007 to December 2015. Pregnancies, covariates and outcome were identified from national registries for births and hospital contacts. We performed logistic regression of the risk of severe PPD in relation to the number and duration of night shifts, spells of consecutive night shifts, and short shift intervals during the first 32 pregnancy weeks. Analyses were adjusted for age, body mass index, socioeconomic status, parity, sickness absence three months prior to pregnancy, and prior diagnosis of severe depression.

Results The study cohort comprised 25 009 singleton pregnancies from 19 382 workers. The majority were nurses or physicians. Overall, we did not observe an increased risk of PPD for any of the dimensions of night work analyzed. We found, however, an increased risk of PPD (adjusted odds ratio 2.08, 95% confidence interval 1.09–4.00) among women who stopped working night shifts after the first pregnancy trimester (N=3094).

Conclusion Overall, our results do not support night work during pregnancy as a risk factor for severe PPD among hospital employees. However, we observed a 2-fold increased risk of PPD among women who stopped working night shifts after the first pregnancy trimester. This may reflect the influence of the healthy worker survivor effect and warrants further attention.

This article refers to the following texts of the Journal: 2011;37(5):402-410  2015;41(3):268-279  2018;44(4):403-413  2018;44(5):512-520
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